Blood and Marrow Transplant (BMT) for Sickle Cell Disease

This handbook was developed to answer common questions about BMT. Please share any questions you may have after reviewing this brochure with your health care team. In the past, only children who had major complications from their sickle cell disease (such as a stroke) were eligible for BMT. Since we know most children do very well after BMT using a matched sibling donor, more children are undergoing BMT today. In addition, we are now learning that adult sickle cell patients can tolerate BMT better than we expected with positive results, particularly those with a matched sibling donor. Most children and many adults with sickle cell disease may be eligible for BMT if they have a matched sibling donor. What if I or my child do not have a matched sibling?   Abstract source