Allogeneic Genoidentical Stem Cell Transplantation in Children With Sickle-cell Anemia and Cerebral Vasculopathy

Clinical Trial
Study Details
Enrollment
63
Interventions
Description

Stem cell transplantation

Name
Stem cell transplantation
Type
Procedure
Description

Transfusion program

Name
Transfusion program
Type
Procedure
Phase
N/A
Status
COMPLETED
Study ID #
NCT01340404
Study Type
Interventional
Summary

The aim of this study is to demonstrate that cerebral velocities assessed by transcranial doppler (TCD) are more significantly decreased by SCT than by long-term transfusion program A multicenter, national, non-randomized, prospective study of paired cohort will be conducted, with 2 groups of exposed (SCT) and non-exposed (TP) patients.

Study Overview
Description

The aim of this study is to demonstrate that cerebral velocities assessed by transcranial doppler (TCD)are more significantly decreased by SCT than by long-term transfusion program A multicenter, national, non-randomized, prospective study of paired cohort will be conducted, with 2 groups of exposed (SCT) and non-exposed (TP) patients. Sixty-three patients will be enrolled, namely 21 sickle-cell patients in the "SCT" group and 42 in the "Transfusion Program (TP)" group

Contacts and Locations
Locations
Facility

CHIC
Créteil
France

GeoPoint
48.79266, 2.46569