Blood Transfusions in Thalassemia Patients, Complications and Adverse Effects

Clinical Trial
Study Details
Enrollment
100
Interventions
Description

Summary of immediate and late adverse effects of blood transfusions

Name
Clinical medical record summary
Type
Other
Phase
N/A
Status
COMPLETED
Study ID #
NCT00971880
Study Type
Observational
Summary

Patients suffering from Thalassemia or another hemoglobinopathies required regular blood transfusions. The complications and adverse effects of blood transfusions can be classified as immediate and late. Among the immediate effects the most common are allergic reactions and fever, besides congestive heart failure in patients with cardiomyopathy. The late effects are mostly related to blood transmitted infections like HIV or Hepatitis C infections.

The purpose of this study is to summarize the data of those complications in a cohort of 100 patients receiving regular blood transfusion.

Study Overview
Description

About 100 patients aged several months to 50 years are treated in the Pediatric Hematology Unit, most of those patients receive blood transfusions monthly. The adverse reactions were routinely recorded during each transfusion. All the patients were also screened annually for the incidence of blood transmitted infections principally HIV and Hepatitis C. All those records will be systematically screened and all the immediate or late adverse reactions and complications related to blood transfusions will be summarized.

A second goal of this study will be to control the staff strictness related to the ministry of health protocol dealing to blood transfusions.

Contacts and Locations
Locations
Facility

Pediatric Hematology Unit and Pediatric Dpt B - HaEmek Medical Center
Afula 18101
Israel

GeoPoint
32.60907, 35.2892