Evolution of Sickle Cell Maculopathy

Clinical Trial
Study Details
Enrollment
34
Phase
N/A
Status
COMPLETED
Study ID #
NCT07877753
Study Type
Observational
Summary

To investigate retrospectively the longitudinal evolution of vascular defects in patients with typical or atypical forms of SCM.

Study Overview
Description

Several questions regarding this SCM are still unsolved. Its physio pathogenic mechanisms are not clearly understood. In addition, the mean age of onset and the evolution of these retinal and vascular defects have not been fully studied. Recently, "atypical" forms of SCM have been reported, in which there are areas of reduction or disappearance of retinal vascularization at the level of the superficial and deep plexuses but without retinal atrophy on OCT. At last, it remains unclear whether SCM evolved over time or remained stable with age The investigators will retrospectively analyze the longitudinal evolution of vascular defects and retinal thickness in typical or atypical forms of SCM using OCT and OCT-A images. OCT-A images will be processed using the AngioTool64 software to obtain vascular density in SCP and DCP. A 5% variation in vascular density will be considered as significant, regardless of its direction.

Contacts and Locations
Locations
Facility

Hopital Européen Georges Pompidou
75015 Paris
France

GeoPoint
48.85341, 2.3488