Clinical Trial
Study Details
Enrollment
44
Interventions
Description
Vascular measures : reactive hyperaemia index (RHI) assessed by Endo-PAT, central aortic blood pressure, aortic augmentation index, carotid-femoral pulse wave velocity
Name
micro- and macro-circulatory vascular remodelling measures not practice in routine care
Type
Procedure
Description
Biological measures : Plasma DNA level, NETs (plasma nucleosome levels), Microparticules (MPs) (total, associated with red blood cells, neutrophils, platelets), haem (total and bound to MPs), Myeloperoxydase and elastase activity, neutrophils/DNA, Annexin A5, RNA and TSP1
Name
Biological measures not practice in routine care
Type
Procedure
Phase
N/A
Status
COMPLETED
Study ID #
NCT02721472
Study Type
Interventional
Summary
The purpose of this study is to evaluate the relationship between plasma DNA levels and micro- and macro-circulatory vascular remodelling in patients with sickle cell disease
Study Overview
Conditions
Contacts and Locations
Locations
Facility
Hôpital Avicenne
93009 Bobigny
France
GeoPoint
48.90982, 2.45012