RElated Haplo-DonoR Haematopoietic stEm Cell Transplantation for Adults With Severe Sickle Cell Disease

Clinical Trial
Study Details
Enrollment
120
Interventions
Description

Stem cell transplant from bone marrow or peripheral blood from haploidentical donor using standard nationally approved transplant procedure.

Name
Haploidentical stem cell transplantation
Type
Procedure
Description

Standard medical care may include any currently available therapies for SCD patients. These may or may not include regular elective transfusion therapy or medications such as hydroxycarbamide.

Name
Standard medical care
Type
Other
Phase
Phase 3
Status
RECRUITING
Study ID #
NCT05392894
Study Type
Interventional
Summary

The purpose of this clinical trial is to evaluate the clinical and cost effectiveness of Haploidentical Stem Cell Transplantation (SCT) for adults with severe sickle cell disease (SCD), who have failed other therapies or are intolerant of existing therapies or require chronic transfusions to prevent on-going complications of SCD.

Study Overview
Conditions
Contacts and Locations
Locations
Facility

King's College Hospital
London
United Kingdom

GeoPoint
51.50853, -0.12574
Status
Recruiting