A Study of the Safety, Blood Levels and Biological Effects of GBT440 in Healthy Subjects and Subjects With Sickle Cell Disease

Clinical Trial
Study Details
Enrollment
133
Interventions
Description

GBT440 will be administered as oral capsules

Name
GBT440
Type
Drug
Description

Matching placebo will be administered as oral capsules

Name
Placebo
Type
Drug
Phase
Phase 1
Status
COMPLETED
Study ID #
NCT02285088
Study Type
Interventional
Summary

The purpose of this study is to assess the safety, tolerability, pharmacokinetic, and pharmacodynamic effects of GBT440 compared with placebo in healthy subjects and subjects with sickle cell disease (SCD).

Study Overview
Contacts and Locations
Locations
Facility

Guy's Hospital
London
SE1 9RT
United Kingdom

GeoPoint
51.50853, -0.12574